Challenges in implementing CD4 testing in resource-limited settings

Viral load testing in resource-limited settings.

Challenges and opportunities for the implementation of virological testing in resource-limited settings

Though the advantages of routine virological monitoring for patients on anti-retroviral therapy have been established, cost and complexity limit its full implementation. Monitoring is important for diagnosing virological failure early on, before the development of drug resistance mutations, and to trigger early adherence interventions. Simple and cost-effective viral load tests that facilitate ...

Resuscitation in resource-limited settings.

Intrapartum-related hypoxia leading to deaths and disabilities continues to be a global challenge, especially in resource-limited settings. Primary prevention during labour is likely to have a significant impact, but secondary prevention with focus on immediate basic stabilization at birth can effectively reduce a large proportion of these adverse outcomes as demonstrated in the resource-rich s...

Challenges of Endocrine Function Testing in Resource Poor Settings

The endocrine system controls the flow of information between cells and tissues, governed by complex regulatory mechanisms (1). Hormones exert widespread influences on various metabolic processes which ensure regulatory, morphogenic and integrative function (2). Signs and symptoms of endocrine disorders span the entire clinical spectrum. Manifestations of endocrine diseases are frequently due t...

Duplicate analysis method: a cheaper alternative to commercial IQC materials in limited resource settings for monitoring CD4 testing

BACKGROUND India has a large number of HIV infected patients being followed up at anti-retroviral therapy (ART) centers. The patients are regularly offered CD4 count estimation for deciding their eligibility for ART initiation as well as for monitoring response to ART, making CD4 count estimation a very critical test. Hence, quality control of CD4 testing is utmost important for ultimate succes...